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Dr. Enas Mohamed Kasem :: Publications: |
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| Title: | Effect of Dipeptidyl Peptidase-4 Inhibitor and angiotensin II type 1 receptor blocker
on renal function in D-galactose induced Aging in male rats and possible relation
between their effects.
|
| Authors: | Enas M. Kasem1 , Eman S. Abdelghany 1* , Mona A. Said 1 , Ahmed I. Agamy1 , Naglaa Y.Nafia1 |
| Year: | 2025 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | Local |
| Paper Link: | Not Available |
| Full paper | Enas Mohamed Kasem_2.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Background: Aging induces structural alterations in the kidney and impairs its functionality. The progression of renal aging is intricately influenced by oxidative stress. Research has shown that plasma DPP-4 activity increases across various organs with aging. Additionally, heightened renin-angiotensin system activity during normal aging may contribute to chronic kidney disease (CKD)sequential progression. Objective:Toevaluate potential synergistic effects of angiotensin II type 1 (Ang II type 1) receptor antagonists and DPP-4 inhibitors in D-galactose-induced aging in male rats, as well as their potential renoprotective effects.Materials and Methods: Thirty-five adult male albino rats were randomly divided into five groups: Group I (control), Group |
