Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by an increase in the
serum blood glucose levels. DM resulted from defects in insulin secretion, action, or both of
them. The chronic hyperglycemia resulted from diabetes can lead to irreversible damage,
dysfunction and failure of various organs. Glycosidic compounds namely, saponins, are
shown to have potential therapeutic benefits and are theorized as an alternative medication
in decreasing serum blood glucose level in patients they suffering from diabetes. This review
article aimed to elucidate the antidiabetic activity of saponins as well as showed their merit
that makes them ideal for antidiabetic remediation. |