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Dr. Zeinab Ibrahim Helmy Elshawarby :: Publications:

Title:
Prognostic Significance of Renin and Erythropoietin (Proteins Related to Renin Angiotensin system Pathway) Expression in Clear Cell Renal Cell Carcinoma (Immunohistochemical Study)
Authors: Zeinab I. Elshawarby*1, Eman A. Saad1, Hiam A. Eleleimy2, Kareem Ali El Attar3, Hanan Ahmed1
Year: 2025
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper Zeinab Ibrahim Helmy Elshawarby_pre 2 vol 99; Zeinab I. Elshawarby-1.pdf
Supplementary materials Not Available
Abstract:

Background: Clear cell renal cell carcinoma (ccRCC) is considered the most common histopathological subtype and constituting nearly 70% of all primary renal cell carcinomas. Dysregulation of proteins related to Renin-Angiotensin System (RAS) could offer a new prognostic indicator in this malignant neoplasm. Objective: This study aimed to demonstrate renin (REN) & erythropoietin (EPO) immunohistochemical expression in ccRCC cases & their expression was correlated with the clinicopathological data & survival of the studied cases to explore their potential prognostic role. Material and methods: This retrospective research carried upon 30 cases ccRCC immunohistochemically stained with REN and EPO & the results to be correlated with different clinicopathological variables and patient's survival.

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