Background: Papillary breast neoplasms are heterogenous group of breast diseases consisting of wide range of benign, atypical and malignant lesions. Evaluation of such papillary neoplasms is considered one of the most problematic issues in diagnosis of breast pathology depending on H&E only as they need different interventional treatment modalities. Aim of study: To differentiate papillary breast lesions depending on immunohistochemical staining of P63, SMA, CK14, chromogranin and ER. Materials and Methods: An Immunohistochemical study of P63, SMA, CK14, chromogranin and ER were conducted on 75 cases of different papillary breast neoplasms; papilloma (20 cases ) , DCIS ( 25 cases ) , solid papillary carcinoma ( 12 cases ), intracystic papillary carcinoma ( 11cases) and invasive micropapillary carcinoma (7 cases) |
