The chamomile is a good source of phenolic and flavonoid compounds that act as a natural antioxidant.
This study was designed to investigate the role of chamomile (CH) against gamma radiation (six gray) induced
hepatotoxicity and renal toxicity. Liver markers, kidney function, lipid profile and oxidative stress Enzymes, i.e.
MDA, CAT, SOD, and GSH were measured after radiation. The obtained results showed that oral
administration of chamomile extract (100mg /kg B.w) orally daily for four weeks , significantly decrements in
the levels of transaminase enzyme in the serum of rats , as soon as significantly decrements in the total lipids
,triglyceride and total cholesterol levels in serum of rats. Also improvement in kidney function through
decrements in the creatinine and urea levels in serum comparing with irradiated group. Significant increments in
the antioxidant enzymes (SOD and CAT) and GSH concentration. On the contrary, significant decrements in
total free radical and MDA in blood and Liver tissues comparing with irradiated group. The present study
suggests that chamomile extract has an antioxidant effect to radio protective effect. hence, chamomile is considered as source of natural antioxidant against gamma radiation effects. |
