Serum sodium is common in cirrhotic patients and can predicts prognosis in cirrhosis and its addition to the
model for end-stage liver disease (MELD) score and may improve the prognostic accuracy. The aim of the present study
was to analyze the characteristics of serum sodium in decompensated cirrhosis and to assess the prognostic value of
serum sodium in the prediction of mortality at 3 and 6 months and to compare the prognostic ability of the model for
end-stage liver disease (MELD) score and other Na-containing MELD scores models for prediction of mortality. This
study was conducted on 200 patients with decompansated cirrhosis (child B & C),patients were divided into two groups
according to their serum sodium group(1)include patients with Na≤125,group(2) include patients with Na>125, Patients
were evaluated, and their medical and laboratory profiles were evaluated and the severity of liver disease was assessed
using Modified Child score ,and seven MELD scores models(MELD, MELD-Na, MELDNa, iMELD, uKELD, MESO
index, and uMELD, The outcome was assessed at the 3- and 6- month for prediction of mortality. This study found that
mortality among hyponatremic patients was more than non hyponatremic at both 3 and 6 month time point, and sodium
containing-MELD scores models had better prognostic value for prediction of both 3 and 6 month mortality. The
incorporation of Na into the MELD may enhance its prognostic accuracy. |
