Introduction
Coronaviruses are a large family of viruses that lead to diseases in animals or
humans.
Objective
To assess clinical, radiological, and laboratory criteria, as well as treatment of
patients hospitalized with coronavirus disease 2019, and the relation to radiological
progression and hospital stay.
Patients and methods
This study was a prospective observational study conducted in an isolation sector in
a private hospital in Saudi Arabia. Data were obtained from electronic records.
Results
A total of 30 patients were enrolled (24 males and six females), and their mean age
was 51.2±15.05 years. The presenting symptoms were fever (83.3%), cough
(33.3%), shortness of breathing (26.7%), body aches (16.7%), and sore throat
(10%). Chest radiograph was abnormal in 76.6%. C-reactive protein (CRP) was
high at 112.59±140±0.50 mg/l, and serum ferritin was 763.21±652.18 μg/l. Lactate
dehydrogenase (LDH) was higher than normal at 312.86±161 U/l. Mean D-dimer
was 0.97±1.11 μg/ml. international normalized ratio was 1.09±0.194. Fibrinogen
was high at 575.32±220.08 mg/dl, and activated partial thromboplastin time was
37.94±17.46 s. There was a strong positive correlation between serum ferritin and
temperature, LDH, and aspartate transaminase. CRP had a strong positive
correlation with alanine transaminase, total leukocytic count, lymphocytes, and
neutrophil/lymphocyte ratio. Hospital stay was positively correlated with ferritin.
LDH was negatively correlated with lymphocytic count. The correlation between
radiological course and laboratory follow-up was poor. |
