Reinforced concrete (RC) slabs are essential structural elements, but their performance can be weakened by unplanned openings introduced after casting. This study explores the flexural behavior of RC two-way slabs with openings, strengthened using innovative techniques through nonlinear finite element modeling in ABAQUS 6.14. The model was validated with experimental results [1], followed by a parametric study on 54 slab specimens. Key variables included opening shapes, strengthening materials (CFRP, GFRP), techniques (NSM, EBR, INNER), rod-end shapes, and FRP sheet configurations. Results showed that double rectangular openings performed best. CFRP sheets increased ultimate load by 36–38%, INNER technique improved strength by 2–6% over NSM, and anchored GFRP sheets enhanced load by 31–35%. Hooked rods raised capacity by 5–10%, and FRP sheets placed at corners of openings added 3–5% more capacity. These findings highlight the significant influence of opening geometry and reinforcement strategies on improving the structural performance of RC slabs |