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Dr. khaled salim :: Publications:

Title:
The effect of percentage of immature oocytes at the time of oocyte retrieval on intracytoplasmic sperm injection outcomes
Authors: Mohamed Mohamed, Khaled Salama, Nadira Elsaid and Mohsen Nossir
Year: 2014
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
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Local/International: International
Paper Link: Not Available
Full paper Not Available
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Abstract:

Objective The aim of this study was to evaluate the role of the percentage of retrieved immature oocytes on intracytoplasmic sperm injection (ICSI) outcomes. Patients and methods A total of 100 ICSI cycles were included in this prospective evaluation. Patients were divided into two groups. Group A included patients with the percentage of mature (M2) oocytes more than 50%, and group B included patients with the percentage of mature oocytes (M2) less than 50% of the total retrieved oocytes. The impacts of the percentages of GV and MI oocytes were assessed on the rates of fertilization, implantation, embryo grading, and pregnancy rate. Results Implantation rate appeared to be significantly high; the implantation rate in group A was 33.2%, versus 17.8% in group B (P =0.036). Fertilization rate also appeared to be significant; it was 71.63% for group A and 48.58% for group B (P =0.049). There was statistical difference between group A and group B as regards embryo grading (D3). A positive b-human chorionic gonadotropin test followed by fetal heart beat detection occurred in 46% of group A and in 34% of group B patients. It was statistically significant (P= 0.049). Conclusion Our data demonstrated that the percentage of immature oocytes may be useful in the prognosis of ICSI outcome. If the percentage of immature oocytes is higher than 50%, the fertilization was significantly lower.

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