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Dr. Hussein Mohamed Elhusseiny Ali Elbayoumi :: Publications:

Title:
Ultrasound assessment of botulinum toxin-A (BOTOX) injection into adult Arabian dromedary camels’ lips: efficacy in detection and localization
Authors: Mohamed Marzok, Jamal Hussen, Mahdi Al Dhafiri, Sherif Saleh, Hussein M El-Husseiny, Mohamed W El-Sherif, Adel I Almubarak, Mohamed Salem
Year: 2025
Keywords: Aesthetic, BOTOX, Camel, Cosmetic, Ultrasound
Journal: BMC Veterinary Research
Volume: 21
Issue: article number 336
Pages: article number 336
Publisher: Springer Nature
Local/International: International
Paper Link:
Full paper Hussein Mohamed Elhusseiny Ali Elbayoumi_s12917-025-04757-1.pdf
Supplementary materials Not Available
Abstract:

Background Ultrasound imaging has become an invaluable tool in veterinary medicine, particularly in guiding injections and visualizing soft tissue structures. Recently, ultrasonography has been used in camel practice to detect cosmetic fillers, particularly in aesthetic evaluations. However, previous applications lacked a controlled experimental background. This study is the first to experimentally assess the effectiveness of ultrasound in detecting and localizing botulinum toxin (BOTOX) injections in camels, using two different doses, from the time of injection until the toxin’s effect becomes undetectable. Objective The objective of this study was to assess the efficacy of ultrasound in detecting and localizing botulinum toxin injection sites in camels’ lips. Methods This study involved 18 adult Arabian dromedary camels (9 Magateer and 9 Majaheem breeds) from the Camel Research Center, King Faisal University. The camels, aged 4.3 ± 1.3 years and weighing 405.5 ± 20.6 kg, were randomly assigned to three treatment groups (6 camels each). Treatments included 100 IU and 200 IU of botulinum toxin type A, and a control of 5 ml sterile saline, administered to the upper and lower lips. Morphological changes, inflammation, and lip thickness were assessed weekly for two months. Ultrasound examinations and hematological and biochemical analyses were conducted at specified intervals. Data were analyzed using two-way repeated-measures ANOVA and Tukey’s test, with significance set at p 

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