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Dr. Hussein Mohamed Elhusseiny Ali Elbayoumi :: Publications: |
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| Title: | Decoding the role of miRNAs in multiple myeloma pathogenesis: A focus on signaling pathways |
| Authors: | Amr Mohamed Yehia, Elsayed GE Elsakka, ..., Hussein M El-Husseiny, ...., Ahmed S Doghish |
| Year: | 2023 |
| Keywords: | Not Available |
| Journal: | Pathology-Research and Practice |
| Volume: | 248 |
| Issue: | 154715 |
| Pages: | 154715 |
| Publisher: | Elsevier |
| Local/International: | International |
| Paper Link: | |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in regulating gene expression in MM. Several non-coding RNAs have been demonstrated to regulate MM pathogenesis signaling pathways. These pathways might regulate MM development, apoptosis, progression, and therapeutic outcomes. They are Wnt/β-catenin, PI3K/Akt/mTOR, P53 and KRAS. This review highlights the impending role of miRNAs in MM signaling and their relationship with MM therapeutic interventions. |
