BACKGROUND:
Fluorosis is an endemic problem in many countries of world. This study was designed to see the effect of fluoride on the reproductive system and to see the role if any of vitamin D or E supplementation on it.
MATERIALS AND METHODS:
Forty-eight male adult albino rats were divided into six equal groups. Group I was fed on standard diet& water, Group II control treated control, Group III on sodium fluoride (NaF) 20 mg/kg body weight, Group IV on NaF + Vitamin D, Group V on NaF + vitamin E, and Group VI on NaF + vitamin D + vitamin E.
RESULTS:
In Group III (fed on sodium fluoride), there was significant decrease in sperm coun, motility and serum testosterone compared to control group. That was also evident on testicular histopathology. With vitamin D supplementation, there was a significant improvement in the sperm count (P |
