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Prof. Evat Isaac :: Publications: |
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| Title: | Novel synthesis of phthalazine derivatives as antimicrobial agents |
| Authors: | Yvette Issac, Eman El-Karim, Shafie Donia, Mohamed Behalow |
| Year: | 2002 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
Reaction of 4-(phenoxathiin-2-yl)-1-oxy or mercaptophthalazines 2a, c with phthalyl or tosylamino acids 3 and 4 has been found to yield 5, 6a-j. Hydrazinolysis of 5, 6a-e furnished amino derivatives 5, 6k-o. Some of the newly synthesized products were tested for their antimicrobial activities. |














