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Dr. Eman Ibrahim Sadek Elgendy :: Publications: |
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| Title: | Significance of Toll-like receptor 4 ( TLR4 )& liver fatty acid-
binding protein (L-FABP) expression in Hepatocellular carcinoma:
an immunohistochemical study
|
| Authors: | 1. Eman Ibrahim Sadik El-Gendy ,2. Prof. Dr. Reda Mohamed Salem El badawy ,3. Prof. Dr. Ranih Zakaria Amer ,4. Prof. Dr. Taghreed Abd Elsamee Abd Elaziz ,5. Prof. Dr. Hala Adel Agina |
| Year: | 2020 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | Local |
| Paper Link: | Not Available |
| Full paper | Eman Ibrahim Sadek Elgendy_manuscript-Eman Elgendy revision 1.docx |
| Supplementary materials | Not Available |
| Abstract: |
Back ground: Persistent inflammatory conditions can induce tumorigenesis . It is therefore very important to explore the molecular mechanisms involved in progression from chronic hepatitis to cirrhosis to HCC - to identify factors useful for the development of effective therapies that improve patient survival . Aim of the study : Evaluation of TLR-4 and L-FABP expression in cases of chronic hepatitis, cirrhosis and HCC and correlate them with clinicopathological parameters. Methods: A retrospective , immunohistochemical study was performed on 50 liver cases;32 cases of HCC, 10 cases of Chronic hepatitis C, and 8 cases of cirrhosis. Results: There was statistical significant increase in TLR-4 expression in HCC than both chronic liver hepatitis and cirrhosis(P |
