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Ass. Lect. Eman Mahmoud fawzy Atta :: Publications: |
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| Title: | Losartan pretreatment versus treatment on Ischemic Acute Renal Injury in Rats |
| Authors: | Mohamed-Ahdy A.A. Saad (1), Rezk A. Sanad (2), Samia M. El-Shiaty (2) and Safwa M. Sorour (2),Eman M. Fawzy (2) |
| Year: | 2019 |
| Keywords: | Losartan, Pretreatment, Acute renal tissue injury. |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Eman Mahmoud fawzy Atta_05-Rev. of Literature.doc |
| Supplementary materials | Not Available |
| Abstract: |
Angiotensin receptor blockers (ARBs) and converting enzyme inhibitors (ACEIs) are have multiple indications other than hypertension. One of these indications is acute renal tissue injury. Comparative study between the protective effect of ARB pretreatment and treatment against an acute kidney injury is needed. Transient bilateral renal ischemia rat model was used to produce acute tissue injury and to test the protective effect of losartan. Serum creatinine, activated partial thromboplastin time (aPTT) and renal tissue injury score are evaluated. Losartan treated group had important more significant reno-protective effect than that of the losartan pretreated-treated group. |
