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Prof. Deena A Elshabrawy :: Publications: |
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| Title: | EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool |
| Authors: | Evan Colletti,* Deena El Shabrawy,*,1 Melisa Soland,*‖ Takashi Yamagami,*,2 Saloomeh Mokhtari,*‖ Craig Osborne,† Karen Schlauch,‡§ Esmail D. Zanjani,* Christopher D. Porada,*‖ and Graça Almeida-Porada*‖, |
| Year: | 2013 |
| Keywords: | crypts of Lieberkühn, transcriptome, Musashi-1, epithelial, Lgr5, transplant, niche |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
To identify human bone marrow stromal cell (BMSC) subsets with enhanced ability to engraft/contribute to the resident intestinal cellular pool, we transplanted clonally derived BMSCs into fetal sheep. Analysis at 75 d post-transplantation showed 2 of the 6 clones engrafting the intestine at 4- to 5-fold higher levels (5.03±0.089 and 5.04±0.15%, respectively) than the other clones (P |
