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Dr. Ashraf A. A. Abdel-Fattah :: Publications: |
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| Title: | Aminoalkylation of nitriles by iminium ions generated in situ |
| Authors: | Alan R. Katritzky,a,* Ashraf A. A. Abdel-Fattaha and Peter J. Steelb,* |
| Year: | 2006 |
| Keywords: | Aminoalkylation; N-(a-Aminoalkyl)benzotriazoles; b-Aminoalkyl nitriles. |
| Journal: | Tetrahedron Letters |
| Volume: | 47 |
| Issue: | Not Available |
| Pages: | 1465–1467 |
| Publisher: | Elsevier Ltd |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Ashraf Abdelfattah_Aminoalkylation.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Aminoalkylation of a series of primary and secondary nitriles with N-(a-aminoalkyl)benzotriazoles 1 (derived from a variety of secondary amines and aldehydes) proceeds smoothly providing the corresponding b-aminoalkyl nitriles 5a–j in 66–97% yields. |
