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Dr. Ashraf A. A. Abdel-Fattah :: Publications: |
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| Title: | Benzotriazole-mediated amidoalkylations of nitroalkanes, nitriles,
alkynes and esters |
| Authors: | Alan R. Katritzky,a* Ashraf A. A. Abdel-Fattaha,b, and Ilhami Celika,c |
| Year: | 2007 |
| Keywords: | Amidoalkylation, N-(β-nitroalkyl)amides, N-(β-cyanoalkyl)-amides, N-acylpropargylamines, β-N-acylamino acids |
| Journal: | ARKIVOC |
| Volume: | xi |
| Issue: | Not Available |
| Pages: | 96-113 |
| Publisher: | ARKAT USA, Inc. |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Ashraf Abdelfattah_amidoalkylations.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Reactions of readily available and stable N-(α-amidoalkyl)benzotriazoles 1 (derived from a variety of aliphatic, aromatic or heterocyclic aldehydes) with diverse nitroalkanes, nitriles, alkynes and esters afforded N-(β-nitroalkyl)amides 4 (54−96%), N-(β-cyanoalkyl)amides 6 (58−88%), N-acylpropargylamines 11 (41−87%) and esters of β-N-acylamino acids 13 (68−96%), respectively. |
