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Prof. Ahmed S. Mohamed :: Publications: |
|
| Title: | Chronic zinc administration improves endothelial cell function
and vascular reactivity in experimentally induced diabetes
mellitus in rats.
|
| Authors: | Mohamed Adel El- Sayed, Nasr N. Nazmy Ahmed S. Mohamed and Sherif W. Mansour. |
| Year: | 2002 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
An exaggerated oxidative stress has been postulated as the link between diabetes mellitus (D.M) and endolhelial dysfunction. This study aimed to investigate the possible therapeutic effect of chronic zinc administration (0.5% in drinking water) on re¬nal artery vascular reactivity and oxidative stress indices viz serum oxidized to reduced glutathione ratio (GSH/GSSG), trolox equivalent antioxidant capacity (TEAC) and lipohy-droperoxides (LPO) in experimentally-induced D.M by strep-tozotocin (STZ) (60 mg/kg i.p single dose) in rats. Using Dop-pler technique in this study indicated that chronic zinc administration significantly (p |
