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Dr. Ahmed Samy Abdel-Azim Saad :: Publications:

Title:
Yeast Cells as Antioxidant-Producing Probiotics: Can they emulate Vitamin E on in-vitro protection of human spermatozoa against oxidative stress?
Authors: Sahar-Eissa A., Saad A. S., Gamal Enan, El-Dougdoug K. A
Year: 2016
Keywords: Antioxidant activities (AOA); Reactive Oxygen specimens (ROS); baker’s Yeast; Vitamin E; in-vitro sperm activation
Journal: Advances in Environmental Biology
Volume: 10
Issue: 9
Pages: 60-68
Publisher: AENSI
Local/International: International
Paper Link: Not Available
Full paper Ahmed Samy Abdel-Azim Saad_new sahar yeast.pdf
Supplementary materials Not Available
Abstract:

Oxidative stress- associated defective sperm function is one of the commonest causes of male infertility, and until recently, it is difficult to evaluate and treat. Overcoming of such oxidative stress status (OSS) by suitable antioxidants sure may help those infertile patients. It is well established that Vitamin E is one of the major membrane protectant against reactive oxygen species (ROS). This study aimed to determine the effect of supplementation of Ham’s F10 media with Vitamin E and comparing the results with Baker’s Yeast (Saccharomyces cerevisiae) extraction, which according to EFSA (The European Food Safety Authority) has a QPS (Qualified Presumption of Safety) status, so it was selected to be our probiotic model. Statistically significant positive influence towards sperm reproductive potential has been revealed in both supplementations of Vitamin E and Baker’s Yeast extraction. The sperm vitality, motility percent, and grade of motility were significantly increased (P

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