Purpose: Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal tract and is the
third most common cancer worldwide after lung and breast cancers, CRC was the 6th cancer in Egypt. This work
was designed to study patient and disease characteristics, medical treatment option and response of all colorectal
cancer patients presented in Menofiaoncology department between 2005 and 2010. Methods: in this retrospective
study, we analyzed the clinical reports of all patients who had a clinical and histopathological diagnosis of colon and
rectal cancer presented to Menofia university clinical oncology department, between March 2005 till December
2010. Results: 84 patients admitted to oncology department from 2005 to 2010 patients with overall incidence about
1.6% of all patients admitted to Menofiaoncology department. Of these, 47 patients (56%) were diagnosed by colon
cancer (group 1) and 37(44%) patients were diagnosed by rectal cancer (group 2). 35.7% (30 patients) were less than
50 years. The median age at diagnosis for colon cancer (group 1) patients was 49 years old and for rectal cancer
group (group 2) was 52 years. There was male predominance.poor performance status, advanced stage, presence of
metastases and elevated CA 19.9 are associated with poor survival in colon cancer group and advanced stage and
disease progression at initial response in rectal cancer group. Conclusion: colon cancer is more common than
rectalcancer, with clear male predominance. It is frequent in patients less than 50 years and urban than rural areas.
Patients with colon cancer have better overall survival than rectal cancer. Advanced stage, presence of metastases
and elevated CA 19.9 are associated with poor survival in colon cancer group and advanced stage and disease
progression at initial response in rectal cancer group.
[Suzy. F. GoharSuzan AAl Hassanin, Mohamed El-Assal and Ahmed M. Hussein. Clinico-Epidemiology Study of
Colorectal Cancer in Menofia University Oncology Department. Nat Sci 2015;13(11):98-105]. (ISSN: 1545-
0740). http://www.sciencepub.net/nature. 14. doi:10.7537/marsnsj131115.14. |
