Purpose This study aimed to compare cochlear function in patients with chronic suppurative otitis media (CSOM) with and
without cholesteatoma and to identify clinical predictors of mixed hearing loss.
Methods A retrospective comparative study conducted at the Otorhinolaryngology Department, Benha University Hospitals,
Egypt, from April 2024 to April 2025. Sixty-two patients with unilateral CSOM and complete audiologic and radiologic
data were included, comprising 30 with cholesteatoma and 32 without. Evaluations included pure-tone audiometry, speech
reception threshold (SRT), speech discrimination score (SDS), and temporal bone computed tomography. Cholesteatoma
severity was staged using the EAONO/JOS classification. Multivariate regression analyses were performed to identify factors
associated with mixed hearing loss and air- and bone-conduction pure-tone averages (PTA), with bone-conduction PTA
serving as a surrogate for cochlear involvement.
Results Disease duration was significantly longer in the cholesteatoma group (P = 0.023), while other baseline characteristics
were comparable. Hearing metrics (PTA, SRT, SDS) did not differ significantly between groups. Multivariate analysis
identified advancing age and longer disease duration as independent predictors of mixed hearing loss, whereas the presence
of cholesteatoma was not.
Conclusion Cholesteatoma was associated with longer disease duration but was not independently associated with measurable
cochlear involvement, based on the audiometric measures and cross-sectional design employed. Age and disease
chronicity were the primary determinants of audiometric |
