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Dr. Abdelmotaal Abdelmajeid El-Shiekh Abdelmotaal Abdelmajeid :: Publications: |
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| Title: | Novel Fluorescent Aminoxy Acids and Aminoxy Hybrid Peptides
SYNTHESIS 2011, No. 1, pp 0083–0090 |
| Authors: | Alan R. Katritzky, Abdelmotaal Abdelmajeid, Srinivasa R. Tala, M. S. Amine, Peter J. Steel |
| Year: | 2011 |
| Keywords: | fluorescence - acylations - amino acids - aminoxy acids – peptides |
| Journal: | Synthesis |
| Volume: | No. 1 |
| Issue: | Not Available |
| Pages: | 83-90 |
| Publisher: | © Georg Thieme Verlag Stuttgart ˙ New York |
| Local/International: | International |
| Paper Link: | |
| Full paper | Abdelmotaal Abdelmajeid El-Shiekh Abdelmotaal Abdelmajeid_Thieme E-Journals - Synthesis _ Abstract.html |
| Supplementary materials | Not Available |
| Abstract: |
a-Aminoxy acid conjugates and hybrid a-aminoxy dipeptide conjugates showing blue to green fluorescence (with quantum yields 0.23–0.71) were synthesized (75–92% yield) from N-Acylbenzotriazoles. 7-Methoxycoumarin derivatives were obtained(quantum yields j 0.35–0.71) that could be suitable for peptide assays. The wavelengths of the absorption maxima (lAbs) and the fluorescence emission maxima (lEm) and the quantum yields (j) of some coumarin-3-ylcarbonyl aminoxy acid conjugates were comparable to those of the analogous amino acid derivatives. |
