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Dr. Ebtehal Maher Abdel Aal El-sayed :: Publications: |
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| Title: | Significance of expression of PD-L1, VEGF and CD8+ T cells in ovarian serous carcinoma: an Immunohistochemical study |
| Authors: | Omneya Y. Bassyoni a , Ebtehal M. Abdel Aal a, Ahmed Khalil b |
| Year: | 2023 |
| Keywords: | PD-L1, VEGF and CD8+T cells. |
| Journal: | Benha medical journal |
| Volume: | 40 |
| Issue: | 3 |
| Pages: | 745-758 |
| Publisher: | Not Available |
| Local/International: | Local |
| Paper Link: | |
| Full paper | Ebtehal Maher Abdel Aal El-sayed_BMFJ-Volume 40-Issue 3- Page 745-758 ovary.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Background: Ovarian cancer is a lethal gynecological malignancy worldwide. The immune system plays a key role in preventing tumor development. Angiogenesis and immune evasion are vital for ovarian cancer progression and metastasis. Aim: This work aimed to evaluate the expression of PD-L1, VEGF and CD8 +T cells in ovarian serous carcinomas and correlate them with clinic-pathological variables. Material and methods: An Immunohistochemical study of PD-L1, VEGF and CD8+ T cells was performed on 50 cases of ovarian serous carcinomas. Results: PD-L1 & VEGF were over-expressed with statistical significance , in higher grade (P |
