Samy Ali Hussein Aziza|Publications

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Prof. Samy Ali Hussein Aziza :: Publications:

Research Fields

endotoxemia, hepatic toxicity, liver fibrosis and steatohepatitis

diabetes and insulin resistance

ulcerative colitis and gastritis, acute pancreatitits

epilepsy and brain stroke

rats

lung cancer, colon cancer, mammary cancer, hepatocarcinogenesis

obesity and hyperlipidemia, atherosclerosis and hypercholesterolemia

Number of publications is 179

Title

1-Chemopreventive, apoptotic, antiangiogenic efficacy of Hesperidin via mitigation of epigenetic alterations of global DNA methylation and targeting microRNA in a rat model of hepatocellular carcinoma

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2-Potential therapeutic and apoptotic impact of ginger and ginger nanoparticles against liver preneoplastic lesions development by inhibition of oncogenic miRNA-221 and initiation of Bcl-2/ caspase 3 signaling pathways

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3-Chemotherapeutic and antiangiogenic activity of Ginger and Ginger nanoparticles in hepatocarcinogenesis -induced in rats via activation of miRNA-29 and attenuation of FGF2/ HGF/ TGF-β1 signaling pathways

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4-Biochemical and Molecular Alterations of Micro RNA 125b and Micro RNA 489-3p as diseases biomarkers in Hepatitis C Virus (HCV)

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5-Molecular and biochemical analysis of MicroRNA-125b and MicroRNA489-3p in chronic hepatitis B virus

Abstract

6-Protective Effect of Spirulina against Aspartame Induced Oxidative Stress and Molecular Gene Brain damage

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7-Resveratrol-Selenium Nanoparticles Alleviate Neuroinflammation and Neurotoxicity in a Rat Model of Alzheimer's Disease by Regulating Sirt1/miRNA-134/GSK3β Expression

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8-Wound healing treatment of local insulin injection with topical chitosan/zinc oxide nanocomposite membrane in diabetic rat model.

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9-Wounds healing activities of topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats through activation of growth factors and suppression of matrix metalloproteinase expressions

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10-Grape seed proanthocyanidin extract or spirulina platensis alleviates blood biochemical and hepatic molecular derangements of experimentally-induced thyroid dysfunction in rats

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11-Spirulina platensis and Grape Seed Proanthocyanidin Extract ameliorates hepatic impairment in Carbimazole-induced hypothyroidism in male rats via caspase 8/Bcl-2 signaling pathway

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12-The potential ameliorative mechanisms of spirulina platensis or grape seed proanthocyanidin extract against thyroid disruptors and epigenetic micro- RNA derangements in L-thyroxine -induced hyperthyroidism in rats

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13-Hesperidin and Rosemary extract alleviates apoptosis and alterations of DNA methyltransferase and targeting microRNA in a rat model of diabetic cardiomyopathy.

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14-Rosemary and hesperidin alleviate cardiac dysfunction and alter cellular signaling pathways in experimental model of diabetic cardiomyopathy

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15-The role of hesperidin and rosemary leaves extract on myocardium glucose transporter 4 pathway for attenuation of diabetic cardiomyopathy

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16-Wound healing acceleration using topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats via modulation of genes expression targeting angiogenesis

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17-Beneficial anti-inflammatory and anti-arthritic activities of Grape seed proanthocyanidin extract in Freund's Complete Adjuvant-induced Rheumatoid arthritis in rats

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18-Biochemical studies on the effect of probiotic in experimentally induced ulcerative colitis in rats

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19-Therapeutic potential and hepatoprotective activity of proanthocyanidinand clopidogrel in non-alcoholic fatty liver disease-induced rats

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20-Grape seed proanthocyanidin extract and anti-platelet drug (clopidogrel) alleviates non-alcoholic fatty liver disease via inhibition of hepatic inflammation in rats

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21-Biochemical and Hematological alterations associated with Doxorubicin induced toxicity in Rats

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22-Beneficial effects of Omega-3 polyunsaturated fatty acids in treatment of non-alcoholic fatty liver disease in rats

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23-Role of Asparagus racemosus root in the amelioration of hepatocellular carcinoma in rat

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24-The protective effects of Spirulina against Non-alcoholic fatty liver disease induced by high fat diet in rats

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25-Protective and therapeutic role of nano-curcumin against hepatocarcinogenesis in rats

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26-Mesenchymal stem cells proliferation augmentation by preconditioning with resveratrol (In vitro Study)

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27-Selenium nanoparticles coated with resveratrol ameliorates the neurobiochemical abnormalities by attenuating oxidative stress and improving neurotransmissions in AlCl3-induced Alzheimer’s model of rats

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28-Evaluation of reno-protective effect of grape seed proanthocyanidin extract on Cyclosporine A- induced Nephrotoxicity by mitigating inflammatory response, oxidative stress and apoptosis in rats

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29-Proanthocyanidin ameliorates ethanol -induced gastric mucosal erosion by attenuating inflammatory response, oxidative stress and apoptosis in rats

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30-Biochemical role of probiotics in improving cell proliferation and regulating proinflammatory cytokine-mediated oxidative damage of ethanol-induced gastric mucosal injury in rats

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31-Thymoquinone suppressed Cyclosporine A- induced Nephrotoxicity in rats via antioxidant activation and inhibition of inflammatory and apoptotic signaling pathway

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32-Lycopene mitigates experimental colitis in rats via inhibiting oxidative stress mediated inflammation and apoptosis

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33-Curcumin and/or Hesperidin alleviates oxidative stress and hormonal alterations in a rat model of cyclophosphamide-induced premature ovarian failure

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34-Therapeutic Role of Curcumin Loaded Magnetic Nanoparticles Against Gamma-Irradiation Hazards in Rats

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35-Attenuating Effect of Spirulina platensis against Mycotoxin Induced Oxidative Stress and Liver Damage in Male Albino Rats

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36- Moringa oleifera ameliorates lipid metabolic disorders, oxidative stress and the inflammatory status in high fat diet-induced obesity in rats

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37-Potential Role of Thymoquinone in Imidaclopride Induced Testicular Toxicity in Male Albino Rats

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38-The Anti-inflammatory and Anti-apoptotic Role of Crocin against Expression of MMp-9, TIMP-1, MCP-1, Caspase-3, PPARα in Heart Tissue, and Metamorphoses of MicroRNA 188 in Hyperhomocysteinemic Rats

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39-Attenuating effect of spirulina platensis and alpha-lipoic acid against aspartame induced oxidative stress and brain damage in rabbits

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40-The potential Anti-Inflammatory and antioxidant activities of Proanthocyanidins in acetic acid–induced ulcerative colitis in rats

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41-The potential anti-inflammatory effect of Omega-3 polyunsaturated fatty acids on experimentally induced ulcerative colitis in rats

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42-Cytoprotective, anti-apoptotic and anti-inflammatory effects of lycopene against mercuric chloride –induced hepatorenal injury in rats: Involvement of TNF-α /NF-κβ/ and p53 signaling pathways

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43-Phytochemical analysis and Antiproliferative activity of lotus peregrinus L. against MCF7 (breast carcinoma cell line)

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44-): Apotent chemopreventive effect of diethyl ether extract of lotus peregrinus L.on apoptosis associated proteins and oxidative stress markers in mammary tumor –induced in rats.

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45-Safety and /or Toxicity of Acute Dual Propolis and Ginger co- treatment in female albino Rats

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46-Role of Ginger as Anti-inflammatory and Anti-apoptotic in Protection of Liver Damage Induced by Metalaxyl Fungicide in Male Albino Rats

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47-The Role of Lycopene as Antioxidant and Anti-inflammatory in Protection of Oxidative Stress Induced by Metalaxyl.

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48-The ameliorative effect of Proanthocyanidins against Streptozotocin induced diabetic nephropathy in rats

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49-Lycopene and its potential role in diabetic nephropathy induced in rats

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50-Attenuating effect of N-acetylcysteine on apoptosis associated with imidaclopride induced testicular damage in male albino rats

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51-Antioxidant potential, anti-inflammatory and hepatoprotective effect of curcumin in a rat model of hepatotoxicity

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53-Biochemical Role of Folic Acid Loaded Magnetic Nanoparticles Versus Gamma Irradiation In Rats

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54-Biochemical Role of Curcumin Loaded Magnetic Nanoparticles Versus Gamma Irradiation in Rats

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55-Biochemical effect of fisetin on experimentally induced liver damage in rats

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56-Biochemical effect of leuprolide, cabergoline and some herbals on ameliorating polycystic ovaries syndrome

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57-Antiobesity activity and hypolipidemic effect of Proanthocyanidins in rats fed a high fat diet

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58-Moringa Oleifera improve lipid metabolic disorders in obesity induced oxidative stress in rats

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59-Avocado Oil Attenuates Diethylnitrosamine Induced-Hepatic Carcinogenesis

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60-A Potent Antioxidants Property of Moringa Oleifera on Mycotoxin Induced Oxidative Stress in Rats

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61-The Potential Protective Effect of Spirulina Platensis against Mycotoxin Induced Oxidative Stress and Liver Damage in Rats

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62-Biochemical effect of curcumin on experimentally induced myocardial injury in rats

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63-Proanthocyanidin inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogensis model

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64-Lycopene Attenuated Nitrosodiethylamine-Induced Hepatocarcinogenesis by Modulating the Metabolic Activation and Detoxification Enzymes

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65-Moringa olifera Attenuated Nitrosodiethylamine-Induced Hepatocarcinogenesis by Modulating the Metabolic Activation and Detoxification Enzymes

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66-Spirullina inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogensis model

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67-Saponins and their potential role in diabetes mellitus

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68-Saponin ameliorate diabetes in STZ-diabetic rats

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69-Preservability of rabbit semen after chilled storage in tris based extender enriched with different concentrations of Propolis ethanolic extract (PEE)

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70-Biochemical effect of resveratrol on Lipids profile and hepatic oxidative stress in experimentally induced obesity in female rats

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71-The Potent Antioxidant Alpha Lipoic Acid

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72-Can Stem Cells Ameliorate the Pancreatic Damage Induced by Streptozotocin in Rats?

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73-Resveratrol ameliorates the biochemical changes in fructose induced insulin resistance in rats.

Abstract

74-Anti-inflammatory activity and ameliorative role of curcumin and alpha-lipoic acid on L-arginine induced acute pancreatitis in rats

Abstract

75-Biochemical evaluation of cytoprotective and anti-inflammatory effect of spirulina platensis and melatonin against fluoride induced brain injury and oxidative stress in rats

Abstract

76-Biochemical changes of chilled rabbit semen diluted in tris based extender enriched with different concentrations of Moringa olifera leaves extract

Abstract

77-Biochemical evaluation of the combination of pegylated IFN-α2b and ribavarin therapy of Egyptian patients suffering from Hepatitis C Virus

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78-The Potential Role of α-lipoic acid in Diabetes Mellitus

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79-Effect of pomegranate peel methanolic extract on oxidative/antioxidant status of chilled diluted rabbit semen

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80-Neurodegeneration and oxidative stress induced by tramadol administration in male rats: The effect of its withdrawal

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81-Ameliorating role of resveratrol on biochemical changes in experimentallyinduced liver fibrosis in rats

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82-Spirulina platensis protects against L-methionine induced hyperhomocysteinemia by abrogation of oxidative stress markers, hyperhomocysteine and inflammation in rats

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83-The Potential protective effect of crocin against hyperhomocysteinemia induced oxidative stress in rats.

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84-Effect of tramadol drug on some biochemical and immunological parameters in albino male rats; evaluation of possible reversal following its withdrawal

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85-Role of antioxidant and anti-inflammatory of Ginger (Zingiber officinal Roscoe) against metalaxyl induced oxidative stress in rats.

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86-Potential protective effects of Quercetin on metalaxyl-induced oxidative stress, impaired liver functions and hepatotoxicity in rat

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87-Chemopreventive Effect of Silymarin in N-Nitrosodiethylamine Induced Hepatocellular Carcinoma in Rats Via Modulation of Inflammatory Mediators, Caspase -3, Oxidative Damage and Antioxidant Status In Liver Tissues

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88-Biochemical Effect of Silymarin Treatment on Blood and Tissue Parameters in Experimental non Alcoholic Steatohepatitis in Rats

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89-The Ameliorative Antioxidant Role of Quercetin in Experimental Model of non Alcoholic Steatohepatitis in Male Rats

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90-ALPHA-LIPOIC ACID PROTECTS RAT KIDNEY AGAINST OXIDATIVE STRESS-MEDIATED DNA DAMAGE AND APOPTOSIS INDUCED BY LEAD.

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91-Evaluation of the Protective Role of Flaxseed Oil on Inflammatory Mediators, Antioxidant Defense System and Oxidative Stress of Liver Tissue in Hypercholesterolemic Rats

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92-Ameliorative Effect Of Curcumin On Hepatic Oxidative Stress, Antioxidant Status, Cardiac Markers Enzymes And Inflammation In High Cholesterol Diet- Induced Hypercholesterolemia In Rats

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93-Evaluation of Gastroprotective Effect and Anti-Inflammatory Role of Resveratrol against Gastric Mucosal Alterations in Experimental Model of Gastritis in Rats

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94-Chemopreventive effect of omega- 3 fatty acids in N-nitrosodiethylamine Induced hepatocellular carcinoma in rats

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95-Caspase-3, Bcl-2, p53, CYP1A1 and COX -2 as a potential target in chemoprevention of Benzo (a) pyrene-induced lung carcinogenesis in mice: Role of thymoquinone

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96-Preventive Effect of Resveratrol against Brain Mitochondria DNA Damage, Lipid Peroxidation, Inflammation and Seizures Induced by Kainic Acid in Mice

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97-Chemopreventive Role of Curcumin in benzo(A)pyrene induced Lung Carcinogenesis in mice via-modulation of Bcl-2, p53, Caspase-3, Cyp1A1, COX-2 and antioxidant defense system in Lung tissues

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98-Neuroprotective Effect of Curcumin on Kainic Acid Model of Epilepsy in Male Swiss Albino Mice

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99-Curcumin ameliorates Ethanol induced Gastric Mucosal Erosion in Rats via alleviation of Oxidative Stress and Regulation of Pro-Inflammatory Cytokines and NF-kappa B activation

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100-Gastroprotective and Antioxidant Activities of Rutin against Ethanol-induced Gastric Mucosal Erosion in Rats via suppression of Inflammation, Oxidative Stress and Apoptosis in Stomach tissues.

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101-Anti-diabetic activity of Holothuria thomasi saponin

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102-Evaluation of cytoprotective effects of N-acetyl cysteine and silymarin on hepatic tissue against arsenic induced inflammation and oxidative stress in rats.

Abstract

103-Synthesis of new 7-benzothiazol-2-yl quinolone derivatives as antitumor agents

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104-Biochemical study on the effect of alpha-lipoic acid on lipid metabolism of rats fed high fat diet.

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105-Biochemical alterations in erythrocytes membrane lipid in experimentally induced atherosclerosis and their modulation with chitosan in rats

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106-METABOLIC EFFECTS OF TAURINE ON EXPERIMENTALLY INDUCED HYPERLIPIDEMIA IN RATS

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107-Hypolipidemic effect of curcumin in hyper-cholesterolemic rats

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108-Beneficial effect of flaxseed oil on lipid metabolism in high cholesterol diet fed rats

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109-FATTY ACIDS COMPOSITION ABNORMALITIES OF RATS SCIATIC NERVE IN STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY

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110-BIOMARKERS OF OXIDATIVE STRESS OF SCIATIC NERVE TISSUES IN EXPERIMENTAL DIABETIC NEUROPATHY

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111-PROTECTIVE EFFECT OF L-CARNITINE ON METABOLIC DISORDERS, OXIDATIVE STRESS, ANTIOXIDANT STATUS AND INFLAMMATION IN A RAT MODEL OF INSULIN RESISTANCE

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112-PROTECTIVE EFFECT OF GREEN TEA EXTRACT ON CYCLOSPORINE A- INDUCED NEPHROTOXICITY IN RATS

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113-GASTRO PROTECTIVE, ANTIAPOPTOTIC AND ANTI-INFLAMMATORY EFFECT OF ALPHA-LIPOIC ACID ON ETHANOL INDUCED GASTRIC MUCOSAL LESIONS IN RATS

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114-PROTECTIVE EFFECT OF CURCUMIN ON ANTIOXIDANT DEFENSE SYSTEM AND OXIDATIVE STRESS IN LIVER TISSUE OF IRON OVERLOADING RATS

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115-AMELIORATING ROLE OF RUTIN ON OXIDATIVE STRESS INDUCED BY IRON OVERLOAD IN HEPATIC TISSUE OF RATS

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116-PROTECTIVE EFFECTS OF ALPHA-LIPOIC ACID AND MELATONIN AGAINSTCADMIUM-INDUCED OXIDATIVE STRESS IN ERYTHROCYTES OF RATS

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117-RENOPROTECTIVE EFFECT OF DIETARY FISH OIL ON CYCLOSPORINE A- INDUCED NEPHROTOXICITY IN RATS.

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118-ANTI-INFLAMMATORY AND ANTI-OXIDANT EFFECT OF RUTIN ON 2, 4, 6-TRINITROBENZENESULFONIC ACIDINDUCED ULCERATIVE COLITIS IN RATS

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119-Gastro Protective, Antiapoptotic And Anti-Inflammatory Effect Of Rutin On Ethanol-Induced Gastritis In Rats

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120-BIOCHEMICAL STUDY ON THE PROTECTIVE EFFECT OF CURCUMIN ON THIOACETAMIDE - INDUCED HEPATOTOXICITY IN RATS

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121-Evaluation of Zinc Oxide Nanoparticles For Insulin, Insulin Receptors And Insulin Receptors Substrates Gene Expression In Streptozotocin-Induced Diabetic Rats

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122-PROTECTIVE EFFECT OF RUTIN ON SOME BIOCHEMICAL PARAMETERS IN A RAT MODEL OF ENDOTOXEMIA

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123-Ameliorating Role Of Curcumin On Oxidative Stress Induced By Endotoxemia In Rats

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124-Protective Effects Of Alpha-Lipoic Acid Against Lead Induced Oxidative Stress In Erythrocytes Of Rats

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125-Protective Effect Of Zinc Oxide Nanoparticles On Oxidative Stress In Experimental - Induced Diabetes In Rats

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126-Pyruvate attenuate lipid metabolic disorders and insulin resistance in obesity induced in rats

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127-Chemopreventive effect of thymoquinone on benzo(a)pyrene-induced lung cancer in male swiss albino mice

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128-Biochemical role of curcumin on kainic acid-induced epilepsy in male swiss albino mice

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129-Resveratrol attenuates kainic acid-induced epilepsy in male swiss albino mice

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130-PROTECTIVE EFFECT OF WHEAT GERM OIL ON BIOMARKERS OF OXIDATIVE STRESS AND INFLAMMATORY RESPONSE IN A RAT MODEL OF ENDOTOXEMIA

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131-Effect of probiotic fermented soy milk and gamma radiation in ameliorating oxidative stress and apoptosis on nitrosoureainduced mammary carcinogenesis

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132-BIOCHEMICAL EFFECT OF ALPHA-LIPOIC ACID AND INSULIN ALONE AND IN COMBINATION ON CHANGES IN THE PHOSPHOLIPID COMPOSITION IN EXPERIMENTAL DIABETIC NEUROPATHY.

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133-Chemopreventive effect of curcumin on oxidative stress, antioxidant status, DNA fragmentation and caspase -9 gene expression in 1,2-dimethylhydrazine-induced colon cancer in rats

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134-Effect of Probiotic Fermented Soy Milk and Gamma Radiation on Nitrosourea-Induced Mammary Carcinogenesis

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135-Protective effect of vitamin E on biomarkers of oxidative stress and inflammatory response in a rat model of endotoxemia.

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136-BIOCHEMICAL EFFECT OF CERTAIN ANTIOXIDANTS ON OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN BRAIN OF EXPERIMENTLLY INDUCED HEPATIC FAILURE IN RATS

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137-Protective effect of Rutin on antioxidant defense system and oxidative stress in Erythrocytes and Brain tissue of Pirimiphos Methyl intoxicated rats.

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138-Antioxidant effect of Thyme on Pirimiphos Methyl induced toxicity in rats.

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139-Ameliorating role of Chlorophyllin on oxidative stress induced by Pirimiphos Methyl in erythrocytes and brain of rats.

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140-protective role of alpha-lipoic acid on some biochemical members of ethanol induced gastric mucosal lesions in rats

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141-Biochemical Relationship Between Vitamin A Content In Liver And Nutrition State

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142-protective role of alpha-lipoic acid on some biochemical members of ethanol induced gastric mucosal lesions in rats

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143-Biochemical, immunomodulatory and antioxidant properties of levamisol at different storage conditions and administration routes.

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144-Biochemical Abnormalities in Brain Tissues during Acute Brain Stroke Induced in Wister Rats

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145-Biochemical Effect Of Alpha-Lipoic Acid On Lipid Profiles, Lipid Peroxidation And Status Of Antioxidant Enzymes In Streptozotocin Induced Diabetes In Rats.

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146-Insulin-mimetic effects of cinnamon extract in Wistar rats.

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147-BIOCHEMICAL EFFECT OF CERTAIN ANTIOXIDANTS ON OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN BRAIN OF EXPERIMENTLLY INDUCED HEPATIC FAILURE IN RATS

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148-Membrane fatty acids in normal and experimentally induced diabetes mellitus in rats.

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149-Effect of cadmium toxicity on some biochemical blood parameters and their modulation with certain natural antioxidants in rabbits.

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150-Biochemical effects of aging on some antioxidant defence enzymes in liver, heart and brain of camels.

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151-BIOCHEMICAL EFFECTS OF CHOLINE AND CARNITINE ON LIPID PROFILE OF LAYING HENS

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152-Effects of garlic oil on certain physiological and biochemical aspects in normal and experimentally induced hyperlipidemia in male albino rats.

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153-EFFECT OF MATERNAL VITAMIN E + SELENIUM STATUS DURING THE PERINATAL PERIOD IN TISSUES ANTIOXIDANTS OF RAT PUPPIES AND THEIR DAMS

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154-Biochemical Effect Of Antidepressant Drugs On Brain And Liver Enzymes In Rabbits

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155-Evaluation of some biochemical and immunological studies in rabbits vaccinated with radiated and formalized inactivated pasteurella multocida vaccines

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156-Biochemical, Immunological And Blood Haematological Changes In Thymectomized Japanese Quail Vaccinated With Newcastle Disease Virus

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157-Metabolic changes concerning the effect of castration on some blood constituents in male rabbits.

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158-SOME BIOCHEMICAL STUDIES DURING ESTROUS CYCLE AND AFTER SYNCHRONIZATION IN BARKI EWES

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159-Effects of Iodine Treated Water and different water sources on some biochemical and physiological changes in blood of New zealand white rabbits

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160-Plasma concentrations of lipids and lipoproteins in newborn kids and female Baladi goats during late pregnancy and onset of lactation.

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161-Effect of late pregnancy and onset of lactation on some trace elements and electrophoretic pattern of serum proteins in female Balady goats and their newborns

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162-Effect of insulin treatment on some metabolic changes on experimentally induced tumor in female mice.

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163-Comparative treatments of anestrous balady cows using PGF 2α and/or PMSG with special reference to some biochemical changes and consequent fertility

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164-Electrophoretic pattern of serum proteins and immunoglobulin (IgG) levels in chickens in relation to Age.

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165-Some Biochemical studies on blood and brain tissues of rats at different Ages

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166-Biochemical analysis of blood and tissues of rats administeredm some food preservatives.

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167-Biochemical Changes in some serum constituents in rats exposed to some carcinogenic compounds.

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168-Some endocrine response to hormonal treatment in cases of anestrum in Buffalo-Cows and reproductive performance relationship

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169-Biochemical Effect of some lipotropic factors on lipid pattern in blood serum of chickens.

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170-Some Biochemical studies on Humans blood before and after exercise.

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171-Effect of ultraviolet rays on Aggressive behavior and hormonal changes in Albino Rats

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172-Biochemical analysis of some blood constituents in female buffaloes during late pregnancy and puerperium.

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173-Oestradiol-17 beta and Progesterone Profiles in Prepubertal Buffalo-Heifers.

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174-Splenectomy in the Camelus Dromedarius: 4-Postoperative immune Response.

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175-Some clinical and Biochemical studies of experimentally infected calves with Trypanosoma evansi.

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176-Hormonal Profile and some minerals in relation to infertility in buffaloes.

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177- Effect of hormonal administration on some trace elements in blood of infertile Buffalo-cows.

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178- Some Physiological and Biochemical studies on imported Horses.

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179-Blood serum lipids of buffalo-calves drinking well water.

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Prof. Samy Ali Hussein Aziza :: Publications: