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Dr. Amira Ibrahim Mansour Ahmed :: Publications: |
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| Title: | Role of Anti-nucleosome Antibodies in the Diagnosis
of Systemic Lupus Erythematosus and as A Marker
for Lupus Nephropathy |
| Authors: | Eman R Abdel Gawad, 1Amira I Mansour, 2Yasser A Abdel Aziz, 2AmlF. Soliman, 2Rasha M. Fawzy |
| Year: | 2014 |
| Keywords: | Anti-nucleosome, Lupus nephritis, SLE |
| Journal: | THE EGYPTIAN JOURNAL OF IMMUNOLOGY |
| Volume: | Vol. 21 |
| Issue: | 1 |
| Pages: | 57-65 |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Amira Ibrahim Mansour Ahmed_6-Eman Ramadan2.pdf |
| Supplementary materials | Not Available |
| Abstract: |
SLE is a heterogeneous disease, characterized by variation in clinical and serological manifestations. This study intended to verify the role of anti-nucleosome (anti-NCS) antibodies in diagnosis of SLE and lupus nephritis and to establish the correlation between antibody reactivity and disease activity. Study subjects included 35 patients diagnosed as SLE and two control groups. While the first is a group with other collagen diseases (n=80), the second included 50 matched apparently healthy subjects. Serum IgG anti-NCS antibodies in all subjects were detected by ELISA. Serum anti-NCS were higher in SLE than in the two control groups (P |
